The Downtick: GLP-1 prices, tracked and verified

Free · twice a week · five minutes

The sticker says $1,349.
The floor says $149.

The Downtick tracks what GLP-1 drugs actually cost in the US and Canada, and explains the business that moves the prices. Every figure carries the date we read it and the sentence on the seller's own page that produced it.

13 editions published · prices re-read every morning

NO. 13SEP 2, 20265 MIN READ
NO. 13SEP 2, 2026

It reaches Dallas.

Two Sundays ago we asked whether the law that reaches peptide sellers would ever be used on American companies, or only on offshore websites. On September 1 the FDA answered, four times, in Texas and elsewhere.

Read the edition
01

Prices, tracked.

Every launch, list price, and generic step, with the numbers verified and dated.

02

The war, called.

Lilly, Novo, and the challengers, covered like the title fight it is.

03

The ripple, reported.

What GLP-1s are doing to food, fitness, insurance, and everything downstream.

The same drug, two countries, one order of magnitude.

Semaglutide lists at $1,349 a month in the United States and sells for C$88 at a Costco counter in Ontario. We track both markets to the same standard, with the date we checked every figure and the method we used, and we report whichever one is moving.

See the board
15.3x
us list price against the lowest verified canadian counter price, same molecule